【学术简介】

工作经历

2008.09-2011.12 江南大学 发酵工程 博士

2012.02-2014.09 江南大学 生物工程学院 讲师

2014.10-至今    江南大学 生物工程学院 副教授，硕士生导师

社会兼职

江苏省教授博士柔性进企业入选者，2012、2013

江苏省第二批“科技副总(企业创新岗)”入选者，2014-2015

【研究领域】

研究方向：发酵工程、生物分离工程

研究内容：ε-聚赖氨酸生物制造与生物合成

【主要论著】（著作和论文，^*代表通讯作者）

[1] Chen XS, Gao Y, Zhen B, Han D, Zhang JH, MaoZG*. Separation and purification of ε-poly-l-lysine from fermentation broth. Process Biochem, 2016,51(1):134-141.

[2] Ren XD, Xu YJ, Zeng X, Chen XS*, Tang L, Mao ZG*. Microparticle-enhanced production of ε-poly-L-lysine in fed-batch fermentation. RSC Adv., 2015, 5:82138-82143.

[3] Zhen B, Chen XS*, Han D, Mao ZG*. An alternative method for the decoloration of ε-poly-L-lysine eluate by macroporous resin in the separation and purification of ε-poly-L-lysine from fermentation broth. Food Bioprod Process 2015,95:332-338.

[4] Zeng X, Chen XS*, Gao Y, Ren XD, Wang L, Mao ZG*. Continuously high reactive oxygen species generation decreased the specific ε-poly-l-lysine formation rate in fed-batch fermentation using glucose and glycerol as a mixed carbon source. Process Biochem 2015,50 (12):1993-2003.

[5] Ren XD, Chen XS*, Zeng X, Wang L, Tang L, Mao ZG*. Acidic pH shock induced overproduction of ε-poly-L-lysine in fed-batch fermentation by Streptomyces sp. M-Z18 from agro-industrial by-products. Bioprocess Biosyst Eng. 2015 38(6):1113-1125.

[6] Ren XD, Chen XS*, Tang L, Zeng X, Wang L, Mao ZG*. Physiological mechanism of the overproduction of ε-poly-L-lysine by acidic pH shock in fed-batch fermentation. Bioprocess Biosyst Eng,2015,38(11):2085-2094.

[7]  Sun QX, Chen XS*, Ren XD, Mao ZG*. Improvement of ε-poly-l-lysine production through seed stage development based on in situ pH monitoring. Appl Biochem Biotechnol, 2015,175:802-812.

[8] Zeng X, Chen XS*, Ren XD, Liu QR, Wang L, Sun QX, Tang L, Mao ZG*. Insights into the role of glucose and glycerol as a mixed carbon source in the improvement of ε-poly-L-lysine productivity. Appl Biochem Biotechnol. 2014,173(8):2211-2224.

[9] Chen XS, Ren XD, Zeng X, Zhao FL, Tang L, Zhang HJ, Zhang JH, Mao ZG. Enhancement of ε-poly-L-lysine production coupled with precursor L-lysine feeding in glucose-glycerol co-fermentation by Streptomyces sp. M-Z18. Bioprocess Biosyst Eng. 2013,36(12):1843-1849.

[10] Chen XS, Mao ZG. Comparison of glucose and glycerol as carbon sources for ε-poly-L-lysine production by Streptomyces sp. M-Z18. Appl Biochem Biotechnol. 2013,170(1):185-197.

[11] Chen XS, Ren XD, Dong N, Li S, Li F, Zhao FL, Tang L, Zhang JH, Mao ZG. Culture medium containing glucose and glycerol as a mixed carbon source improves ε-poly-L-lysine production by Streptomyces sp. M-Z18. Bioprocess Biosyst Eng. 2012,35(3):469-475.

[12] Chen XS, Li S, Liao LJ, Ren XD, Li F, Tang L, Zhang JH, Mao ZG. Production of ε-poly-L-lysine using a novel two-stage pH control strategy by Streptomyces sp. M-Z18 from glycerol. Bioprocess Biosyst Eng. 2011,34(5):561-567.

[13] Chen XS, Tang L, Li S, Liao LJ, Zhang JH, Mao ZG. Optimization of medium for enhancement of ε-poly-L-lysine production by Streptomyces sp. M-Z18 with glycerol as carbon source. Bioresour Technol. 2011,102(2):1727-1732.

[14] 刘庆瑞, 陈旭升*, 曾昕, 韩岱, 毛忠贵*. 链霉菌M-Z18膜蛋白ε-聚赖氨酸降解酶的分离纯化、酶学性质及应用. 微生物学报,2014,54(9):1022-1032.

[15] 孙启星，陈旭升*，任喜东，郑根成，毛忠贵*. 基于pH调节和有机氮源流加调控补料分批发酵过程提高ε-聚赖氨酸产量.生物工程学报,2015,31(5):752−756.

【科研项目】

[1] 国家自然科学青年基金：混合碳源强化生物食品防腐剂ε-聚赖氨酸合成的生理过程机制(31301556), 2014-2016，主持

[2] 江苏省科技支撑计划项目：新型生物食品防腐剂ε-聚赖氨酸高效发酵技术研究(BE2012616)，2012-2015，主持

[3] 江苏省产学研联合创新项目：新型生物食品防腐剂ε-聚赖氨酸高效提取关键技术与集成化研究(BY2013015-11)，2013-2015，第二主持

[4] 工业生物技术教育部重点实验室开放课题：链霉菌依赖低pH环境合成ε-聚赖氨酸的生理机制研究(JUSRP51504)，2015-2016，主持

[5] 企业合作项目2项，主持
 

【荣誉与奖励】

[1]   杜邦工业生物应用科技奖教金，2013

[2]   益海嘉里博士生奖学金，2011

【在读硕、博士人数】

指导在读硕士生2人；协助指导在读硕士生6人，在读博士生4人

【已毕业硕、博士人数】

协助指导硕士毕业生8人，博士毕业生1人

【以上资料更新日期】

2016年1月